▎ 摘　　要

A sensitive and novel electrochemical sensor for detection of bergenin by linear sweep voltammetry (LSV) is presented. This sensor was fabricated by dripping well-dispersed graphene onto glassy carbon electrode (GCE) surface firstly, and then poly(L-lysine) films were subsequently electropolymerized on it to prepare poly(L-lysine)/graphene/GCE. The dynamic detection range of this sensor to bergenin was 4.0 x 10(-8) to 5.0 x 10(-6) mol L-1 and 6.0 x 10(-6) to 1.7 x 10(-5) mol L-1, with the detection limit of 1.0 x 10(-8) mol L-1. A new voltammetric method for determination of bergenin was erected and shows high sensitivity and selectivity, wider linear relationship, very easy surface update and good stability. The proposed sensors were tested for bergenin detection in pharmaceutical tablets with high accuracy and satisfactory recovery results was obtained. In addition, the oxidation mechanism is proposed and discussed, which could be a reference for the pharmacological action of bergenin in clinical studies.