• 文献标题:   Poly (vinyl alcohol)/chitosan/polyethylene glycol-assembled graphene oxide bio-nanocomposites as a prosperous candidate for biomedical applications and drug/food packaging industry
  • 文献类型:   Article
  • 作  者:   MOHAMMADI S, BABAEI A
  • 作者关键词:   surface modification, nanohybrid, characterization, bionanocomposite
  • 出版物名称:   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
  • ISSN:   0141-8130 EI 1879-0003
  • 通讯作者地址:  
  • 被引频次:   14
  • DOI:   10.1016/j.ijbiomac.2022.01.086 EA JAN 2022
  • 出版年:   2022

▎ 摘  要

The graphene oxide (GO) nanoplates and polyethylene glycol-decorated GO (GO-PEG nano-hybrid) were synthesized and characterized by FTIR, Raman, XRD, AFM, FE-SEM-EDAX and MTT assay. Obtained results confirmed the graphite oxidation and also assembly of PEG upon GO plates. The MTT assay indicated that GOPEG nanohybrid enhanced biocompatibility to cells compared to the GO. The GO-PEG nanohybrid was introduced to the polyvinyl alcohol/chitosan carbohydrate (PVA/CS) blends. The bio-nanocomposite were prepared by simple casting method. The GO-PEG nanohybrids demonstrated a significant role in improving thermal, mechanical and antibacterial properties. Accordingly, bio-nanocomposites containing modified GO (PVA/CS/ GO-PEG) exhibited higher glass transition temperature (Tg), Young's modulus, tensile strength, elongation at break and antibacterial properties than nanocomposites containing pure GO (PVA/CS/GO). The biodegradation outcomes indicated that the highest weight loss and degradability is related to the bio-nanocomposite containing modified GO (PVA/CS/GO-PEG), which was also confirmed by FE-SEM micrographs. Therefore, PVA/CS/GOPEG bio-nanocomposites can be a suitable candidate for biomedical applications (tissue engineering, wound dressing) and food-drug packaging industry.