▎ 摘　　要

A novel electrochemical sensor based on graphene and tetraphenylboron-dopamine electroactive material was developed for determination of dopamine which is correlative to some neurogenic disease. Graphene was synthesized by one-step liquid-phase exfoliation of graphite and the tetraphenylboron-dopamine was prepared by precipitation reaction on formation-of ion association complex. The resultant electrode showed better performance in selectivity, sensitivity and narrow potential window comparing with bare graphite electrode and graphite electrode modified by tetraphenylboron-dopamine. In the presence of 1000-fold concentration interference-of ascorbic acid and uric acid, the linear range for dopamine was successfully determined from 1 x 10(-4) to 1 x 10(-10) mol/L with a correlation coefficient of 0.9969. The detection limit was estimated to be 7.39 x 10(-11) mol/L in 3 of signal to noise ratio (S/N = 3). According with successive measurements in 10 times, the relative standard deviation of all results for graphene/tetraphenylhoron-dopamine /graphite electrode still kept in 1.83 %. Moreover, the graphene/tetraphenylboron-dopamine /graphite electrode could be stored for 30 days in 4 degrees C without sharply decease Of its electroactivity. All results clearly prove that this modified electrode is sensitive way for selective determination of dopamine.