• 文献标题:   A New Graphene Derivative: Hydroxylated Graphene with Excellent Biocompatibility
  • 文献类型:   Article
  • 作  者:   SUN J, DENG Y, LI JP, WANG G, HE P, TIAN SY, BU XM, DI ZF, YANG SW, DING GQ, XIE XM
  • 作者关键词:   graphene derivative, hydroxylated graphene, biomaterial, reversible, regeneration
  • 出版物名称:   ACS APPLIED MATERIALS INTERFACES
  • ISSN:   1944-8244
  • 通讯作者地址:   Chinese Acad Sci
  • 被引频次:   23
  • DOI:   10.1021/acsami.6b02032
  • 出版年:   2016

▎ 摘  要

Graphene derivatives (such as graphene oxide and hydrogenated graphene) have been widely investigated because of their excellent properties. Here, we report large-scale (kilogram scale) synthesis of a new unique graphene derivative: hydroxylated graphene (G-OH). The exclusive existence form of oxygen-containing groups in G-OH is hydroxyl, which was verified by spectral characterization and quantitative halogenating reaction. It is very interesting that both the wettability and electrical conductivity show reversible change in halogenating and hydrolysis reaction cycles, which demonstrates the versatility of G-OH. Most importantly, the hydrophilicity and weak inductive nature of G-OH provides a well microenvironment for the cells adhesion and proliferation. On G-OH paper, rat adipose tissue-derived stromal cells exhibited a typical fibroblast-like shape with high rate of increase and survival after 3 day of incubation. This G-OH paper with good mechanical property is expected to be a new biomaterial for bone, vessel and skin regeneration.