• 文献标题:   A three-dimensional hybrid of CdS quantum dots/chitosan/reduced graphene oxide-based sensor for the amperometric detection of ceftazidime
  • 文献类型:   Article
  • 作  者:   PAIMARD G, SHAMSIPUR M, GHOLIVAND MB
  • 作者关键词:   ceftazidime, cds quantum dot, chitosan, reduced graphene oxide, amperometry
  • 出版物名称:   CHEMICAL PAPERS
  • ISSN:   0366-6352 EI 2585-7290
  • 通讯作者地址:  
  • 被引频次:   2
  • DOI:   10.1007/s11696-022-02494-5 EA SEP 2022
  • 出版年:   2023

▎ 摘  要

Ceftazidime (CFZ), an anti-bacterial infection drug, was electrochemically investigated at the surface of CdS quantum dots/chitosan/reduced graphene oxide modified glassy carbon electrode (CdS-QDs/CS/rGO/GCE) in pH 3.0 phosphate buffer solution. The modified electrode was described by scanning electron microscopy, Fourier-transform infrared spectroscopy, electrochemical impedance spectroscopy, and cyclic voltammetry. Graphene oxide was synthesized through Hummers'method, which was electrochemically reduced at GCE. CS was used as the introduction of amino groups onto the surface rGO/GCE. The presence of CdS-QDs on the surface of CS/rGO/GCE improved the responded current of the electrooxidation toward CFZ. Under optimized conditions, amperometry in stirred solutions at the practical potential of 0.86 V displayed a linear range of concentration between 15 nM and 95 mu M of CFZ. The limit of detection was 4.5 nM. The suggested sensor has high sensitivity and good selectivity for determining CFZ in spiked real samples. [GRAPHICS]