• 文献标题:   Graphene as a protein crystal mounting material to reduce background scatter
  • 文献类型:   Article
  • 作  者:   WIERMAN JL, ALDEN JS, KIM CU, MCEUEN PL, GRUNER SM
  • 作者关键词:  
  • 出版物名称:   JOURNAL OF APPLIED CRYSTALLOGRAPHY
  • ISSN:   0021-8898 EI 1600-5767
  • 通讯作者地址:   Cornell Univ
  • 被引频次:   21
  • DOI:   10.1107/S002188981301786X
  • 出版年:   2013

▎ 摘  要

The overall signal-to-noise ratio per unit dose for X-ray diffraction data from protein crystals can be improved by reducing the mass and density of all material surrounding the crystals. This article demonstrates a path towards the practical ultimate in background reduction by use of atomically thin graphene sheets as a crystal mounting platform for protein crystals. The results show the potential for graphene in protein crystallography and other cases where X-ray scatter from the mounting material must be reduced and specimen dehydration prevented, such as in coherent X-ray diffraction imaging of microscopic objects. (C) 2013 International Union of Crystallography Printed in Singapore - all rights reserved