• 文献标题:   Fabrication and Characterization of Graphene-Based Electrochemical Sensors for Glucose Measurement
  • 文献类型:   Article
  • 作  者:   PARK M, CHOI H, PARK Y, LEE W, LEE J, JEON M
  • 作者关键词:   graphene, reduced graphene oxide, glucose oxidase, glucose, polyvinylpyrrolidone, electrochemical sensor
  • 出版物名称:   JOURNAL OF NANOSCIENCE NANOTECHNOLOGY
  • ISSN:   1533-4880 EI 1533-4899
  • 通讯作者地址:   Inje Univ
  • 被引频次:   2
  • DOI:   10.1166/jnn.2015.11231
  • 出版年:   2015

▎ 摘  要

Glucose in the blood is generally measured by electrochemical method using glucose oxidase (GO,) which acts as enzymes and reduced graphene oxide (rGO) composite. The rGO, which has low dispersibility, reduces the sensing capability of sensors. In order to solve this problem, the rGO electrodes with the addition of polyvinylpyrrolidone (PVP) have been reported. However, rGO with low electrical conductivity and mobility is not compatible to the electrochemical system. In this study, graphene with excellent electrical properties was added to PVP protected rGO. The rGO was synthesized using a Hummer and Offeman's method. Graphene was synthesized using chemical vapor deposition (CVD) with a Cu catalyst. Platinum (Pt) electrodes, Ag/AgCl, and PVP protected rGO were used as working electrode, reference electrode, and counter electrode, respectively. Surface morphology and structural properties of graphene were analyzed using atomic force microscopy (AFM), Raman spectroscopy, and Fourier transform infrared spectroscopy (FT-IR). Cyclic voltametry (CV) and I-V probe station were used to analyze the performance of the electrodes. Glucose concentration was systematically varied and the reduction current was monitored using I-V probe station.