• 文献标题:   Preparation of novel molecularly imprinted magnetic graphene oxide and their application for quercetin determination
  • 文献类型:   Article
  • 作  者:   DRAMOU P, ITATAHINE A, FIZIR M, MEHDI YA, KUTOKA PT, HE H
  • 作者关键词:   magnetic graphene oxide, mip, quercetin, mspe, nanomaterial
  • 出版物名称:   JOURNAL OF CHROMATOGRAPHY BANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL LIFE SCIENCES
  • ISSN:   1570-0232 EI 1873-376X
  • 通讯作者地址:   China Pharmaceut Univ
  • 被引频次:   7
  • DOI:   10.1016/j.jchromb.2019.06.007
  • 出版年:   2019

▎ 摘  要

In this work, quercetin (Que) molecular imprinted polymer (MP) material decorated on magnetic graphene oxide (MGO) with high performance was prepared for the first time using a surface-imprinting technique. Magnetic graphene oxide was synthesized using the solvothermal route. Methacrylic acid (MAA) was used as functional monomer, ethylene glycol dimethyl acrylate (EGDMA) as cross-linker; Que. was used as template, for the decoration with MIP. The prepared nanocomposite was examined by different characterization methods including fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), vibrating sample magnetometer (VSM). The adsorption performance was investigated. MGO-MIP was found to have high loading (369 mg g(-1)) and selective capacity making the nanomaterial more performant than previous similar reported nanomaterials. The determination of Que. was carried out by mean of magnetic solid phase extraction method coupled with high-performance liquid chromatography (HPLC) and the extraction conditions studies were also performed out. Under the optimized conditions, MGO-MIP showed great performance for the extraction, separation and determination of Que. in green tea and serum samples, compared to the flavonoid analogs luteolin (Lut) and rutin (Rut) in the same matrix samples.