• 文献标题:   Non-enzymatic glucose sensing by enhanced Raman spectroscopy on flexible 'as-grown' CVD graphene
  • 文献类型:   Article
  • 作  者:   CHATTOPADHYAY S, LI MS, ROY PK, WU CT
  • 作者关键词:  
  • 出版物名称:   ANALYST
  • ISSN:   0003-2654 EI 1364-5528
  • 通讯作者地址:   Natl Yang Ming Univ
  • 被引频次:   6
  • DOI:   10.1039/c5an00546a
  • 出版年:   2015

▎ 摘  要

Unmodified, as-grown few layered graphene on copper substrates have been used for glucose sensing using Raman spectroscopy. Graphene with a stronger 2D band is a better Raman enhancer with significant fluorescence suppression and finer line widths of the Raman signals. The origin of the graphene enhanced Raman spectroscopy (GERS) signal of glucose is attributed to a fractional charge transfer (calculated to be 0.006 using electrochemical parameters) between glucose and graphene aided by a possible pi-pi interaction. Physiological concentrations of glucose (10-500 mg dl(-1)) in PBS have been used for the study. For each glucose concentration, the spectral reproducibility is within 5-25% as calculated by the relative standard deviation of several measurements. The intensity ratio of the 1122 cm(-1) peak of glucose and the 2D peak of graphene varied linearly with the glucose concentration and can be used as a calibration curve for unknown sample measurements.