• 文献标题:   ELECTROCHEMICAL DETECTION OF EPINEPHRINE USING AN L-GLUTAMIC ACID FUNCTIONALIZED GRAPHENE MODIFIED ELECTRODE
  • 文献类型:   Article
  • 作  者:   KANG HZ, JIN Y, HAN Q
  • 作者关键词:   electrochemical sensor, epinephrine, graphene, lglutamic acid, nanocomposite
  • 出版物名称:   ANALYTICAL LETTERS
  • ISSN:   0003-2719 EI 1532-236X
  • 通讯作者地址:   Hebei Normal Univ
  • 被引频次:   11
  • DOI:   10.1080/00032719.2013.876541
  • 出版年:   2014

▎ 摘  要

The development and application of an L-glutamic acid functionalized graphene nanocomposite, modified glassy carbon electrode are reported for the determination of epinephrine. The properties of the nanocomposite were characterized by scanning electron microscopy, ultraviolet-visible absorption spectroscopy, infrared spectroscopy, cyclic voltammetry, and electrochemical impedance spectroscopy. The modified electrode had high sensitivity and strongly catalytic activity for the detection of epinephrine. A linear relationship between the epinephrine concentration and the current response was obtained in the range of 1 x 10(-7) M to 1 x 10(-3) M by differential pulse voltammetry with a limit of detection of 3 x 10(-8) M. The modified electrode was employed to determine epinephrine in urine with satisfactory results.