▎ 摘　　要

In the preset study, ZnO nanoparticles were synthesized by thermal treatment method and the ZnO/SiO2 and ZnO/SiO2/RGO nanocomposites were obtained by polymerization method. The degree of crystallinity, microstructure and phase composition were investigated by using different characterization techniques, i.e., X-ray diffraction, field emission scanning electron microscope, transform infrared spectroscopy and Raman spectroscopy, respectively. The compositions of the samples were determined by Energy dispersive X-ray analysis at room temperature. The surface areas of samples were obtained from nitrogen gas adsorption-desorption isotherms by Brunauer-Emmett-Teller analysis at 77 K. In addition, viability of breast tumor cells and normal 3T3-fibroblasts after exposure to RGO, of ZnO/SiO2 and ZnO/SiO2/RGO were evaluated using MTT assay. RGO had no toxicity and almost all breast tumor cells and fibroblasts were viable after exposure to RGO. Furthermore, the toxic effect of ZnO/SiO2/RGO and of ZnO/SiO2 was more in breast tumor cells compared to normal 3T3 fibroblasts. However of ZnO/SiO2 had a mild effect compared with ZnO/SiO2/RGO.