▎ 摘　　要

A novel type of hierarchical boron/nitrogen co-doped yolk-shell hollow mesoporous carbon nanospheres (Yolkshell B,N-MCNSs) was designed and developed through a simple and direct template method. Specifically, the codoped heteroatoms contribute to enhancing the electric conductivity, surface polarity of carbon framework, and leading to extra sites graft into carbon surface. Subsequently, the introduction of reduced graphene oxide (rGO) as a highly conductive and robust support promotes the electron transport as well as restricts the selfagglomeration of the Yolk-shell B,N-MCNSs. Consequently, the Yolk-shell B,N-MCNSs/rGO exhibits the unique architectural features of both a unique 3D multi-level porous structure and a hierarchical connectivity, providing more active sites for electrochemical reaction and a favorable path for easy penetration of electrons, ions, and biomolecules. Due to the inherent merits of components, and together with unique structural advantages, the obtained Yolk-shell B,N-MCNSs/rGO manifests excellent sensing performance for synchronous detection of xanthine and guanosine with a wide linear range from 9.15 x 10-8 to 1.03 x 10-4 M and 8.22 x 10-8 to 1.28 x 10-4 M, a lower detection limit of 5.03 x 10-8 M and 4.62 x 10-8 M, respectively, and good durability. Additionally, it exhibits outstanding selectivity for common interfering species and satisfactory recoveries in serum which suggests its feasibility for practical application.