• 文献标题:   Theranostic potential of graphene quantum dots for multiple sclerosis
  • 文献类型:   Letter
  • 作  者:   DEMIRDOGEN BC
  • 作者关键词:   biomedicine, drug delivery, nanobiotechnology, nanoparticle, neuroscience, personalized medicine
  • 出版物名称:   MULTIPLE SCLEROSIS RELATED DISORDERS
  • ISSN:   2211-0348 EI 2211-0356
  • 通讯作者地址:  
  • 被引频次:   0
  • DOI:   10.1016/j.msard.2022.104232 EA OCT 2022
  • 出版年:   2022

▎ 摘  要

Nanomedicine offers great promise to solve healthcare problems using nanotechnology. Theranostics provide imaging/diagnosis and therapy simultaneously. Novel agents that target both the neuroinflammation and neu-rodegeneration component of multiple sclerosis (MS) are required. Progress has been achieved in developing smart, surface decorated nanoparticles that effectively transport the therapeutic drug into the central nervous system (CNS). Graphene quantum dots (GQDs) can be traced in vivo by fluorescence imaging due to their unique optical properties. They can also traverse the blood-brain barrier (BBB) and deliver drugs into the CNS. More-over, GQDs have low cytotoxicity and higher biocompatibility. Therefore, GQDs can be utilized to design novel multifunctional nanocarrier theranostic tools for MS.