▎ 摘　　要

The potency of various synthesized graphene nanocomposites, namely, reduced graphene oxide, silver nanoparticles-reduced graphene oxide and silver nanoparticles-reduced graphene oxide@Lysine, to interact with forensically relevant drugs i.e., nitrazepam and diazepam, was examined under similar physiological conditions using fluorescence spectroscopy. Also, various characterization techniques such as X-ray spectroscopy, Fourier-transform infrared spectroscopy and Raman spectroscopy were employed to confirm the synthesis of graphene and its nanocomposites. The values of binding constant and Stern-Volmer binding constant influenced by temperature were investigated. They were supposed to be related to quenching process between graphene nanocomposites and forensically relevant drugs which were mainly determined by the combination of static and dynamic quenching. Further, the thermodynamic parameters of the nanocomposite were also studied at different temperatures, and Delta G was calculated.