• 文献标题:   Characterization of Scaffold Prepared by Blending Nanobioactive Glass and Graphene Oxide-Gelatin Hydrogel Solutions for Bone Tissue Engineering
  • 文献类型:   Article
  • 作  者:   SAMAD SA, ARAFAT AA, GAFUR MA, CHOWDHURY AMS
  • 作者关键词:   nanobioactive glas, graphene oxide, scaffold, hydrogel, mechanical property
  • 出版物名称:   JOURNAL OF BIOMATERIALS TISSUE ENGINEERING
  • ISSN:   2157-9083 EI 2157-9091
  • 通讯作者地址:   Univ Dhaka
  • 被引频次:   4
  • DOI:   10.1166/jbt.2015.1359
  • 出版年:   2015

▎ 摘  要

A biologically promising material with improved mechanical property has been developed successfully. In this study graphene oxide of varying amount were incorporated into a gelatin-nanobioactive glass (nBG-Gel) matrix through a freeze drying technique. The compressive strength test was carried out to determine the reinforcement effect of GO and it demonstrated that nBG-Gel matrix with GO shows a remarkably higher compressive strength and a compressive modulus than those of the bare. The porous structure (in terms of pore size and pore interconnectivity) of the composite scaffolds were examined. Morphological characterization revealed the formation of an interconnected porous hybrid of size range of 100 mu m to 600 mu m. The thermal properties of the hybrid were analyzed using Simultaneous Thermal Analyzer (STA). All the experimental results demonstrate that the prepared hybrid scaffold is a potential candidate for bone tissues engineering.