• 文献标题:   Processable conducting graphene/chitosan hydrogels for tissue engineering
  • 文献类型:   Article
  • 作  者:   SAYYAR S, MURRAY E, THOMPSON BC, CHUNG J, OFFICER DL, GAMBHIR S, SPINKS GM, WALLACE GG
  • 作者关键词:  
  • 出版物名称:   JOURNAL OF MATERIALS CHEMISTRY B
  • ISSN:   2050-750X EI 2050-7518
  • 通讯作者地址:   Univ Wollongong
  • 被引频次:   89
  • DOI:   10.1039/c4tb01636j
  • 出版年:   2015

▎ 摘  要

Composites of graphene in a chitosan-lactic acid matrix were prepared to create conductive hydrogels that are processable, exhibit tunable swelling properties and show excellent biocompatibility. The addition of graphene to the polymer matrix also resulted in significant improvements to the mechanical strength of the hydrogels, with the addition of just 3 wt% graphene resulting in tensile strengths increasing by over 200%. The composites could be easily processed into three-dimensional scaffolds with finely controlled dimensions using additive fabrication techniques and fibroblast cells demonstrate good adhesion and growth on their surfaces. These chitosan-graphene composites show great promise for use as conducting substrates for the growth of electro-responsive cells in tissue engineering.