▎ 摘　　要

Molecular dynamics simulations were performed to investigate the dynamic process of DNA segments' adsorption on graphene oxide (GO) in aqueous solution. We find that DNA segments finally 'stand on' GO's surface. Due to energy penalty and electrostatic repulsion, DNA segments cannot lie on the surface of GO with their helical axes parallel to GO's surface. Both pi-pi stacking and electrostatic interactions contribute to their binding affinity between the contacting basepair and GO. The results are of great importance to understand the interactions between DNA segments and GO.