▎ 摘　　要

Chiroselective recognition of important bioactive substances by artificial receptors in biological environments is a topic of great interest from both a biochemistry and analytical application point of view. Therefore, a beta-cyclodextrin modified graphene oxide system was reported, which provided a new enantioselective sensing device for amino acid enantiomers both in vitro and in living cells. The excellent sensing capabilities of this functional graphene oxide in living cells shown here make it a robust candidate for many biological fields, such as intracellular imaging, and intracellular tracking, etc.