• 文献标题:   Highly sensitive and selective fluorescence sensing and imaging of Fe3+ based on a novel nitrogen-doped graphene quantum dots
  • 文献类型:   Article
  • 作  者:   WU DM, QU CJ, WANG JZ, YANG R, QU LB
  • 作者关键词:   ferric ion, fluorescence, nitrogen graphene quantum dot
  • 出版物名称:   LUMINESCENCE
  • ISSN:   1522-7235 EI 1522-7243
  • 通讯作者地址:  
  • 被引频次:   3
  • DOI:   10.1002/bio.4062 EA JUL 2021
  • 出版年:   2021

▎ 摘  要

A novel nitrogen-doped graphene quantum dots (N-GQDs) with a green fluorescence emission was synthesized through microwave method using citric acid and semicarbazide hydrochloride as reactants. The as-synthesized N-GQDs exhibited good stability, excellent water solubility, and negligible cytotoxicity. Due to intermolecular charge transfer, ferric ion (Fe3+) has a strong quenching effect on the N-GQDs. Fluorescence quenching has a linear relationship with the Fe3+ concentration in the range 0.02-12 mu M. The detection limit was 1.43 nM. What is more, it is worth mentioning that the obtained N-GQDs showed high selectivity and sensitivity towards Fe3+. Under the optimum conditions, the addition of 10-fold copper ions and 100-fold other metal ions had no influence on the detection of Fe3+ (0.8 mu M), which indicated a higher sensitivity compared with that of the reported methods. Due to their excellent properties, the obtained N-GQDs was successfully applied for sensing and imaging Fe3+ in water samples and HeLa cells.