• 文献标题:   Stimuli responsive drug delivery systems based on nano-graphene for cancer therapy
  • 文献类型:   Review
  • 作  者:   YANG K, FENG LZ, LIU Z
  • 作者关键词:   nanographene, drug delivery, stimuliresponsive, cancer therapy
  • 出版物名称:   ADVANCED DRUG DELIVERY REVIEWS
  • ISSN:   0169-409X EI 1872-8294
  • 通讯作者地址:   Soochow Univ
  • 被引频次:   156
  • DOI:   10.1016/j.addr.2016.05.015
  • 出版年:   2016

▎ 摘  要

Nano-graphene as a class of two-dimensional sp(2) carbon nanomaterial has attracted tremendous attentions in various fields in the past decade. Utilizing its unique physical and chemical properties, nano-graphene has also shown great promises in the area of biomedicine, for application in biosensing, imaging and therapy. In particular, with all atoms exposed on its surface, nano-graphene exhibits ultra-high surface area available for efficient binding/loading of various biomolecules of interests, and has been widely used as multifunctional nano-carriers for drug and gene delivery. In this review article, we will summarize the recent advances in the development of nano-graphene as stimuli-responsive nano-carriers for drug delivery, as well as the applications of these smart systems for cancer therapy. (C) 2016 Elsevier B.V. All rights reserved.