▎ 摘　　要

A novel molecular imprinted polymer (MIP) as a SPE sorbent was synthesized for fluoxetine through a coprecipitation method. The synthesized polymer was characterized by Fourier transform infrared (FT-IR) spectroscopy and scanning electron microscopy (SEM). The kinetic and adsorption equilibrium was studied. Quantification of fluoxetine was done based on the competitive inclusion complex formation of fluoxetine with phenolphthalein-p-cyclodextrin using fiber optic linear array spectrophotometry. The method exhibited a linear dynamic range of 0.8-10.0 mu g L-1 with a detection limit of 0.03 mu g L-1 and a preconcentration factor of 500. The developed method was successfully applied to determine fluoxetine in various samples. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.