▎ 摘　　要

A novel titanium dioxide-graphene-polyaniline (TiO2-RGO-PANI) hybrid was prepared by the one-pot method and used as a nonenzymatic electrochemical sensor for glucose detection. The composition and structural morphology of the as-prepared composites were determined by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The characterization results showed that TiO2-RGO-PANI is mainly composed of Ti, O, C and N and their weight percentages are 67.68%, 21.57%, 10.70% and 0.05%, respectively, indicating that the TiO2-RGO-PANI composite catalyst has been successfully prepared and presents a poriferous coral structure. A series of electrochemical tests such as cyclic voltammetry tests declared that TiO2-RGO-PANI composite possessed a low limit of detection (LOD) (7.46 mu M), good repeatability, selectivity and stability. In the concentration range of 10-180 mu M, the hybrid presented linear diffusion, and the linear equation was I-pa = 0.21338 + 0.01392 (C/mM), the correlation coefficient R-2 = 0.9912. In addition, the comparison of the merits of this proposed electrode with some recent nonenzymatic glucose sensors indicates that this highly sensitive TiO2-RGO-PANI complex glucose sensor provides a simple, low-cost, nonenzymatic method for glucose detection, and has promising applications in clinical diagnostics and medical analysis.