▎ 摘　　要

We report on the chemiluminescence (CL) of graphene quantum dots (GQDs) induced by direct chemical oxidation. GQDs were prepared by a simple carbonization method and characterized by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy and Raman spectroscopy. It was found that Ce(IV) could oxidize GQDs to produce a relatively intense CL emission. The mechanism of CL generation was investigated based on the fluorescence and CL emission spectra. It was attributed to the radiative recombination of oxidant-injected holes and thermally excited electrons in the GQDs. In order to show the analytical application potential of GQDs-Ce(IV) CL system, it was applied to the determination of uric acid. Under the optimized conditions, the proposed CL system exhibited excellent analytical performance for determination of uric acid in the range of 1.0 x 10(-6) M-5.0 x 10(-4) M with a limit of detection of 5.0 x 10(-7) M. The method was applied to the determination of uric acid in human plasma and urine samples, with satisfactory results. (C) 2014 Elsevier B.V. All rights reserved.