• 文献标题:   Synthesis of short graphene oxide nanoribbons for improved biomarker detection of Parkinson's disease
  • 文献类型:   Article
  • 作  者:   SUN CL, SU CH, WU JJ
  • 作者关键词:   graphene oxide nanoribbon, multiwalled carbon nanotube, unzipping, ascorbic acid, dopamine, uric acid
  • 出版物名称:   BIOSENSORS BIOELECTRONICS
  • ISSN:   0956-5663 EI 1873-4235
  • 通讯作者地址:   Chang Gung Univ
  • 被引频次:   13
  • DOI:   10.1016/j.bios.2014.08.046
  • 出版年:   2015

▎ 摘  要

We demonstrate the microwave-assisted synthesis of short graphene oxide nanoribbons (GONRs) through unzipping cut multiwalled carbon nanotubes (MWCNTs). Transmission electron microscopy and dynamic light scattering spectroscopy were used to examine the length, size, and morphology, i.e. unzipping level, of our various products. The nanotube core and nanoribbon shell can be observed from short GONRs via a modified unzipping recipe. Then the short GONRs were adopted to modify the glassy carbon electrode for the electrochemical detection of ascorbic acid (AA), uric acid (UA), and dopamine (DA). Compared to other nanomaterials, cyclic voltammograms of short GONRs show higher anodic oxidation currents for AA, UA, and DA. The detection limits of three analytes are 26, 98, and 24 nM, respectively, in amperometric current-time measurements. Especially, the sensitivity for DA is improved to be 40.86 mu A mu M-1 cm(-2). The improved detection signals are due to the increased active sites of the open ends of short GONRs. Moreover, the width side of short GONRs could be more active than their length side. All above-mentioned results reveal that the short GONRs can provide a novel platform for electrochemically biomarker detection of Parkinson's disease. (C) 2014 Elsevier B.V. All rights reserved.