• 文献标题:   Near-Infrared Light-Triggered Bacterial Eradication Using a Nanowire Nanocomposite of Graphene Nanoribbons and Chitosan-Coated Silver Nanoparticles
  • 文献类型:   Article
  • 作  者:   ZHOU M, GAN HQ, CHEN GR, JAMES TD, ZHANG B, HU Q, XU FG, HU XL, HE XP, MAI YY
  • 作者关键词:   chitosan, silver nanoparticle, graphene nanoribbon, antibiotic, nanocomposite
  • 出版物名称:   FRONTIERS IN CHEMISTRY
  • ISSN:   2296-2646
  • 通讯作者地址:  
  • 被引频次:   2
  • DOI:   10.3389/fchem.2021.767847
  • 出版年:   2021

▎ 摘  要

Bacterial infection is a major threat to human health. However, many antibacterial agents currently used are severely limited due to drug-resistance, and the development of side effects. Herein, we have developed a non-antibiotic nanocomposite consisting of chitosan (ChS) coated silver nanoparticles (AgNPs) and graphene nanoribbon (GNR)-based nanowires for light-triggered eradication of bacteria. The presence of AgNP/ChS significantly enhanced the interactions of the GNR nanowires with Pseudomonas aeruginosa, a clinically common Gram-negative bacterium. Which enables the highly effective photothermal eradication of bacteria by GNR upon near-infrared light irradiation. The nanocomposite was shown to be applicable for the light-triggered eradication of bacterial biofilms and the inhibition of bacterial growth on medical patches used for abdominal-wall hernia surgery.