▎ 摘　　要

The level of fructose is an important indicator alongside the blood glucose level in detecting diabetes mellitus. The development of boronic acid (BA)-modified electrodes are still of interest to researchers in the sensor-based detection systems for fructose. Hence, a novel electro-optical solid-state probe based on fluorogenic dye for saccharide detection was established for the first time. A flexible ITO/PET with nano-metric electrodeposited layers of graphene oxide (GO) was used as a primary electrode. A new selectophore based on boronate-tagged 1,8-naphthalimide (NB) with a planar structure was used to form a composite film with Mg-Al layered double hydroxide (LDH) nanoplatelets. The minimum sheet resistance, uniform morphology, and high electrocatalytic activity of the modified matrix film were obtained in the fifth cycle of the LBL assembled modified electrode ((NB/LD)5/GO/ITO/PET). This solid-state electrode led to electrochemical changes due to the BA and sugar transduction at 0.59 V vs Ag/AgCl in a cyclic voltammetry technique and increased the fluorescence emission. The designed probe indicated good selectivity toward fructose within the range of 10-225 nM at the physiological pH 7.4.