• 文献标题:   Biocomposite Based on Reduced Graphene Oxide Film Modified with Phenothiazone and Flavin Adenine Dinucleotide-Dependent Glucose Dehydrogenase for Glucose Sensing and Biofuel Cell Applications
  • 文献类型:   Article
  • 作  者:   RAVENNA Y, XIA L, GUN J, MIKHAYLOV AA, MEDVEDEV AG, LEV O, ALFONTA L
  • 作者关键词:  
  • 出版物名称:   ANALYTICAL CHEMISTRY
  • ISSN:   0003-2700 EI 1520-6882
  • 通讯作者地址:   Hebrew Univ Jerusalem
  • 被引频次:   26
  • DOI:   10.1021/acs.analchem.5b02949
  • 出版年:   2015

▎ 摘  要

A novel composite material for the encapsulation of redox enzymes was prepared. Reduced graphene oxide film with adsorbed phenothiazone was used as a highly efficient composite for electron transfer between flavin adenine dinudeotide (FAD)-dependent glucose dehydrogenase and electrodes. Measured redox potential for glucose oxidation was lower than 0 V vs Ag/AgCl electrode. The fabricated biosensor showed high sensitivity of 42 mA M-1 cm(-2), a linear range of glucose detection of 0.5-12 mM, and good reproducibility and stability as well as high selectivity for different interfering compounds. In a semibiofuel cell configuration, the hybrid film generated high power output of 345 mu W cm(-2). These results demonstrate a promising potential for this composition in various bioelectronic applications.