▎ 摘　　要

Magnetically separable CuO nanoparticles supported on graphene oxide (Fe3O4 NPs/GO-CuO NPs) is synthesized and characterized for the preparation of propargylamines in EtOH, at 90 degrees C. Fe3O4 NPs/GO-CuO NPs is found to be an efficient catalyst for the A(3)-coupling of aldehydes, amines, and alkynes through C-H activation. Both aromatic and aliphatic aldehydes and alkynes are combined with secondary amines to provide a wide range of propargylamines in moderate to excellent yields. (C) 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.