• 文献标题:   Graphene oxide nanomaterials in the recovery of shoulder joint movement contraction
  • 文献类型:   Article
  • 作  者:   ZHU YY
  • 作者关键词:   graphene oxide, titanium dioxide nanotube, antibacterial ability, mesenchymal stem cell, shoulder joint, recovery
  • 出版物名称:   INTERNATIONAL JOURNAL OF NANOTECHNOLOGY
  • ISSN:   1475-7435 EI 1741-8151
  • 通讯作者地址:  
  • 被引频次:   0
  • DOI:   10.1504/IJNT.2022.128951
  • 出版年:   2022

▎ 摘  要

The drug loading capacity, the drug releasing capacity, and the antibacterial ability of the GO-TiO2 nanotubes were analysed. The results showed that after seven days of culture, the cell adhesion rate on GO-TiO2 surface (79.9%) was obviously higher than that on pure titanium surface (52%) (P < 0.05); the mesenchymal stem cells (MSCs) on GO-TiO2 nanotubes surface were in the form of polymerised colonies, while the MSCs on the surface of pure Ti were in the form of dispersed particles. The drug-loaded GO-TiO(2)nanotube film did not release the drug after eight days, while the drug release time of the drug-loaded GO-TiO2 nanotube film covered by poly(lactide-coglycolide) (PLGA) was extended to 24 days. The antibacterial ability of pure Ti, GO-TiO2 nanotubes, and drug-loaded GO-TiO2 nanotubes was compared as pure Ti < GO-TiO2 nanotubes