▎ 摘　　要

In the current study, it has been shown how to make an electrochemical sensor for measuring the amount of oxymetholone in blood serum samples from bikers using a nitrgen-doped graphene oxide and carbon nanotube nanocomposite (N-doped GO/CNTs). The N-doped GO/CNT nanocomposite was created using the pyrolysis technique, and the GCE was modified by electrochemical deposition. N-doped GO/CNT nanocomposite structural studies employing XRD and SEM analysis revealed that the nanocomposite's corrugated sheet-like shape featured GO nanosheets with CNTs scattered on the nanosheets. The EDX elemental analysis revealed that the N atoms in the GO/CNT structure had been successfully doped. According to electrochemical tests using the DPV approach, the detection limit was established as 0.01 ng/mL, the calibration curve demonstrated a linear relationship to the concentration of oxymetholone from 0 to 114 ng/mL, and the sensitivity was attained at 0.18849 mu A/ng.mL(-1). The linear range and detection limit of the oxymetholone sensor in this work are enhanced and are better than in previous electrochemical reports, according to a comparison of the performance of the electrochemical sensor used in this study and other recently published oxymetholone sensors. Five hours following the race, genuine blood serum samples from four riders were used to test the accuracy and usefulness of N-doped GO/CNTs/GCE for the detection of oxymetholone M. The results showed that the RSD values (3.69% to 4.34%) were appropriate and acceptable for practical analyses in blood serum and clinical samples that were valid and accurate.