• 文献标题:   Zinc oxide surface-functionalized PCL/graphene oxide scaffold: enhanced mechanical and antibacterial properties
  • 文献类型:   Article, Early Access
  • 作  者:   AKHIGAN N, NAJMODDIN N, AZIZI H, MOHAMMADI M
  • 作者关键词:   aminolysi, graphene oxide, immobilization, pcl scaffold, zinc oxide
  • 出版物名称:   INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS POLYMERIC BIOMATERIALS
  • ISSN:   0091-4037 EI 1563-535X
  • 通讯作者地址:  
  • 被引频次:   4
  • DOI:   10.1080/00914037.2022.2100373 EA JUL 2022
  • 出版年:   2022

▎ 摘  要

Porous poly caprolactone (PCL)/graphene oxide (GO) scaffold was fabricated using both particulate and foaming agents to yield better control over pore size. Then, the surface of the PCL/GO scaffold was modified by the aminolysis method for further treatment. Needle-like zinc oxide (ZnO) was synthesized and its antibacterial activity was verified by the disk diffusion method. Next, ZnO immobilized onto the aminolyzed PCL/GO scaffold. The mechanical test demonstrated a pronounced increment of young's modulus for the PCL scaffold. It is expected that such an engineered scaffold has a high potential to be used in tissue engineering with minimal irritation due to infections during implantation.