• 文献标题:   Graphene-Based Biosensors
  • 文献类型:   Article
  • 作  者:   LEBEDEV AA, DAVYDOV VY, NOVIKOV SN, LITVIN DP, MAKAROV YN, KLIMOVICH VB, SAMOILOVICH MP
  • 作者关键词:  
  • 出版物名称:   TECHNICAL PHYSICS LETTERS
  • ISSN:   1063-7850 EI 1090-6533
  • 通讯作者地址:   Russian Acad Sci
  • 被引频次:   6
  • DOI:   10.1134/S1063785016070233
  • 出版年:   2016

▎ 摘  要

Results of developing and testing graphene-based sensors capable of detecting protein molecules are presented. The biosensor operation was checked using an immunochemical system comprising fluorescein dye and monoclonal antifluorescein antibodies. The sensor detects fluorescein concentration on a level of 1-10 ng/mL and bovine serum albumin-fluorescein conjugate on a level of 1-5 ng/mL. The proposed device has good prospects for use for early diagnostics of various diseases.