▎ 摘　　要

A hybrid structure comprised of Cu-BaTiO3-BP-graphene on a BK7 prism as a modified Kretschmann configuration for biosensing application is proposed and numerically analyzed using the transfer matrix method (TMM). Numerical results show that with appropriate optimization of the thickness of copper (Cu), barium titanate (BaTiO3), and the number of layers of 2D materials, the proposed sensor exhibited sensitivity and detection accuracy (DA) as high as 372 deg/RIU and 0.327/ deg, respectively. Here, the well-optimized utilization of BaTiO3, black phosphorus (BP), and graphene over Cu not only protects it from oxidation but also enhances the adsorption of biomolecules. Such enhanced performance would make the design have more applications in the field of biomolecular detection, such as pseudomonas bacteria, and in biosensing applications.