• 文献标题:   Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions
  • 文献类型:   Article
  • 作  者:   DIAO JJ, WANG TT, LI L
  • 作者关键词:   graphene quantum dot, propofol, fluorescence, emulsion
  • 出版物名称:   ROYAL SOCIETY OPEN SCIENCE
  • ISSN:   2054-5703
  • 通讯作者地址:   Xinjiang Med Univ
  • 被引频次:   2
  • DOI:   10.1098/rsos.181753
  • 出版年:   2019

▎ 摘  要

We report a new fluorescent detection method for propofol based on graphene quantum dots (GQDs). Citric acid (CA) was selected as the carbon precursor, and fluorescent GQDs were prepared by carbonizing CA. The product, which efficiently quenched the fluorescence of GQDs, could be obtained through the oxidation of propofol in the presence of horseradish peroxidase and hydrogen peroxide. The fluorescence intensity ratio of GQDs (F/F-0) was positively correlated with the concentration of propofol, which ranged within 5.34-89.07 mg l(-1), the limit of detection was 0.5 mg l(-1) and the limit of quantity was 5.34 mg l(-1). The developed fluorescence method reported in the present study is simple, sensitive, reproducible, and can serve in determining propofol contents in emulsions.