• 文献标题:   Enhanced MRI relaxivity of aquated Gd3+ ions by carboxyphenylated water-dispersed graphene nanoribbons
  • 文献类型:   Article
  • 作  者:   GIZZATOV A, KESHISHIAN V, GUVEN A, DIMIEV AM, QU FF, MUTHUPILLAI R, DECUZZI P, BRYANT RG, TOUR JM, WILSON LJ
  • 作者关键词:  
  • 出版物名称:   NANOSCALE
  • ISSN:   2040-3364 EI 2040-3372
  • 通讯作者地址:   Rice Univ
  • 被引频次:   22
  • DOI:   10.1039/c3nr06026h
  • 出版年:   2014

▎ 摘  要

The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd3+ ions can serve as a high-performance contrast agent (CA) for applications in T-1- and T-2-weighted magnetic resonance imaging (MRI) with relaxivity (r(1,2)) values outperforming currently-available clinical CAs by up to 16 times for r(1) and 21 times for r(2).