▎ 摘　　要

Graphene oxide has great application prospect in many fields due to its unique optical, high surface area, exceptional electronic, thermal and mechanical properties. Taking advantage of the property that graphene oxide can effectively quench the fluorescence of fluorophor including dye, quantum dot and upconversion nanophosphors and various bioanalytical technology, many fluorescent sensors have been developed. In this review, we summarized the principle of fluorescent sensors based on graphene oxide and their application in heavy metallic ion, DNA, protein and small bio-molecule. Moreover, the trends and future perspectives in this research area are also briefly discussed.