• 文献标题:   Sensitive electrochemical detection of dopamine with a DNA/graphene bi-layer modified carbon ionic liquid electrode
  • 文献类型:   Article
  • 作  者:   WANG XF, YOU Z, SHA HL, CHENG Y, ZHU HH, SUN W
  • 作者关键词:   carbon ionic liquid electrode, grapheme, dsdna, differential pulse voltammetry, dopamine
  • 出版物名称:   TALANTA
  • ISSN:   0039-9140 EI 1873-3573
  • 通讯作者地址:   Qingdao Univ Sci Technol
  • 被引频次:   29
  • DOI:   10.1016/j.talanta.2014.04.078
  • 出版年:   2014

▎ 摘  要

A DNA and graphene (GR) bi-layer modified carbon ionic liquid electrode (CILE) was fabricated by an electrodeposition method. GR nanosheets were electrodeposited on the surface of CILE at the potential of -1.3 V and then DNA was further deposited at the potential of +0.5 V on GR modified CILE. Electrochemical performances of the fabricated DNA/GR/CILE were carefully investigated. Then electrochemical behaviors of dopamine (DA) on the modified electrode were studied with the calculated electrochemical parameters. Under the optimized conditions, a linear relationship between the oxidation peak current and the concentration of DA was obtained in the range from 0.1 mu mol/L to 1.0 mmol/L with a detection limit of 0.027 mu mol/L (3 sigma). The modified electrode exhibited excellent reproducibility, repeatability, stability, validation and robustness for the electrochemical detection of DA. The proposed method was further applied to the DA injection solution and human urine samples determination with satisfactory results. (C) 2014 Elsevier B.V. All rights reserved.