▎ 摘　　要

Here we investigated the chitosan (CS)-graphene oxide (GO) supramolecular scaffold and the significant synergistic effect of GO and carbon nanotubes (CNTs) in the structure. To this end, a supramolecular hydrogel was prepared by fulfilling the conditions for intermolecular self-assembly between GO nanosheets and CS chains. Also, CS-wrapped CNTs were incorporated into the system to induce electrical conductivity. Then, the structure was developed to a macroporous scaffold through subsequent lyophilization. The formed architectures were characterized by using dynamic mechanical thermal analysis (DMTA), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), field emission scanning electron microscopy (FE-SEM), and wide angle X-ray diffraction (XRD). The results indicated that the combination of CNTs and GO nanoparticles has a synergistic effect on the distribution and performance of the two nanoparticles. Due to the amphiphilic nature of CS, the presence of each of the nanoparticles improves the interaction of CS with the other, resulted in improving their dispersion into the biopolymeric matrix. Supramolecular properties, convenience and ease of preparation of the scaffolds make them suitable for applications such as biomedical engineering, biosensors, and artificial muscle, especially for cardiac tissue engineering due to their electrical conductivity and high porosity.