• 文献标题:   Highly efficient and scale-up synthesis of propargylamines catalyzed by graphene oxide-supported CuCl2 catalyst under microwave condition
  • 文献类型:   Article
  • 作  者:   XIONG XQ, CHEN HX, ZHU RJ
  • 作者关键词:   propargylamine, a 3 coupling, gocucl2, green chemistry
  • 出版物名称:   CATALYSIS COMMUNICATIONS
  • ISSN:   1566-7367 EI 1873-3905
  • 通讯作者地址:   Univ Huaqiao
  • 被引频次:   27
  • DOI:   10.1016/j.catcom.2014.05.030
  • 出版年:   2014

▎ 摘  要

An efficient, green and practical approach was developed to synthesize propargylamines using recyclable GO-CuCl2 via a one-pot multicomponent aldehyde-alkyne-amine (A(3)) coupling reaction. The propargylamines are readily obtained in good to excellent yields (85-96%) and on multi-gram scale (88%, 150 mmol) under microwave irradiation. GO-CuCl2 could be easily recovered through filtration and reused at least five recycles with no significant decreases in the yields. (C) 2014 Elsevier B.V. All rights reserved.