• 文献标题:   Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
  • 文献类型:   Review
  • 作  者:   XU ZL, PENG MS, ZHANG ZL, ZENG HT, SHI RY, MA XX, WANG LS, LIAO BH
  • 作者关键词:   pancreatic cancer, microrna21, microrna196a, cea, signal amplification, kras gene
  • 出版物名称:   FRONTIERS IN CHEMISTRY
  • ISSN:   2296-2646
  • 通讯作者地址:  
  • 被引频次:   17
  • DOI:   10.3389/fchem.2021.733371
  • 出版年:   2021

▎ 摘  要

Pancreatic cancer is a highly lethal gastrointestinal malignancy. Most patients are already in the middle to advanced stages of pancreatic cancer at the time of diagnosis and cannot be treated completely. As a single-atom planar two-dimensional crystal, graphene's unusual electronic structure, specific electronic properties and excellent electron transport capacity make it uniquely advantageous in the field of electrochemical sensing. In this mini-review, we summarize the potential application of graphene in pancreatic cancer detection. K-Ras gene, CEA and MicroRNA are important in the early diagnosis of pancreatic cancer.