• 文献标题:   Mechanical, microstructural properties and cell adhesion of Sr/Se-hydroxyapatite/graphene/polycaprolactone nanofibers
  • 文献类型:   Article, Early Access
  • 作  者:   ALWAFI R, MANSOUR SF, AHMED MK
  • 作者关键词:   codopant hydroxyapatite, structure, cells attachment, hfb4, se
  • 出版物名称:   JOURNAL OF THERMOPLASTIC COMPOSITE MATERIALS
  • ISSN:   0892-7057 EI 1530-7980
  • 通讯作者地址:   King Abdulaziz Univ
  • 被引频次:   15
  • DOI:   10.1177/0892705720912781 EA MAR 2020
  • 出版年:  

▎ 摘  要

Electrospun nanofibrous scaffolds containing co-dopant of Sr/Se into carbonated hydroxyapatite has been synthesized in situ with graphene (G) nanosheets and carried on polycaprolactone at different contributions of G. The powder and the nanofibrous samples were investigated using X-ray diffraction, transmission electron microscopy, and field emission scanning electron microscopy (FESEM). The FESEM micrographs show that the highest content of G (0.2 G) was formed in non-oriented/rough/cracked fibers with diameters around 0.3-0.4 mu m at the maximum. The tensile strength of nanofibrous scaffolds was improved with the addition of G nanosheets and the maximum tensile strength of 0.2 G was around 6.39 +/- 0.24 MPa, while the minimum cell viability ratio was about 94.4 +/- 3.2% for the free G nanofibers. The in vitro attachment of HFB4 cell lines was investigated and it showed that nanofibrous scaffolds have induced cells to be proliferated and spread on the nanofibrous scaffolds' surface. This behavior of cells growth encourages more investigations for these nanofibrous scaffolds to be promoted for clinical applications.