文献标题: Highly sensitive methyltransferase activity assay and inhibitor screening based on fluorescence quenching of graphene oxide integrated with the site-specific cleavage of restriction endonuclease
文献类型: Article
作 者: JI LJ, CAI ZW, QIAN YD, WU P, ZHANG H, CAI CX
作者关键词:
出版物名称: CHEMICAL COMMUNICATIONS
ISSN: 1359-7345 EI 1364-548X
通讯作者地址: Nanjing Normal Univ
被引频次: 26
DOI: 10.1039/c4cc04428b
出版年: 2014
▎ 摘 要
We report a sensitive and selective approach for the DNA methyltransferase (MTase) activity assay and MTase inhibitor screening by coupling the fluorescence quenching of graphene oxide with site-specific cleavage of a restriction endonuclease.
