• 文献标题:   Application of Graphene in Tissue Engineering of the Nervous System
  • 文献类型:   Review
  • 作  者:   LAWKOWSKA K, POKRYWCZYNSKA M, KOPER K, KLUTH LA, DREWA T, ADAMOWICZ J
  • 作者关键词:   graphene, graphenebased nanomaterial, tissue engineering, nervous system, cell culture
  • 出版物名称:   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
  • ISSN:  
  • 通讯作者地址:  
  • 被引频次:   9
  • DOI:   10.3390/ijms23010033
  • 出版年:   2022

▎ 摘  要

Graphene is the thinnest two-dimensional (2D), only one carbon atom thick, but one of the strongest biomaterials. Due to its unique structure, it has many unique properties used in tissue engineering of the nervous system, such as high strength, flexibility, adequate softness, electrical conductivity, antibacterial effect, and the ability to penetrate the blood-brain barrier (BBB). Graphene is also characterized by the possibility of modifications that allow for even wider application and adaptation to cell cultures of specific cells and tissues, both in vitro and in vivo. Moreover, by using the patient's own cells for cell culture, it will be possible to produce tissues and organs that can be re-transplanted without transplant rejection, the negative effects of taking immunosuppressive drugs, and waiting for an appropriate organ donor.