• 文献标题:   Graphene oxide nanosheets-catalyzed synthesis of novel benzylbarbiturocoumarin derivatives under green conditions
  • 文献类型:   Article
  • 作  者:   ESKANDARI K, KARAMI B
  • 作者关键词:   metalfree catalyst, barbituric acid, 4hydroxycoumarin, aldehyde, green chemistry
  • 出版物名称:   MONATSHEFTE FUR CHEMIE
  • ISSN:   0026-9247 EI 1434-4475
  • 通讯作者地址:   Univ Yasuj
  • 被引频次:   8
  • DOI:   10.1007/s00706-016-1724-8
  • 出版年:   2016

▎ 摘  要

An efficient tricomponent reaction between barbituric acid (or N,N-dimethylbarbituric acid), 4-hydroxycoumarin, and a wide range of aryl aldehydes to obtain novel benzylbarbiturocoumarins is described. Starting materials were successfully condensed via three C-C bond formation by graphene oxide nanosheets as an efficient, metal-free, environmentally safe, and recyclable nanocatalyst to obtain target products. The target products were obtained with high selectivities and yields (80-88 %) in H2O/EtOH (1:1) in the presence of graphene oxide nanosheets (0.005 g) at 80 A degrees C.