• 文献标题:   Direct Electrochemistry of Glucose Oxidase at Reduced Graphene Oxide and -Cyclodextrin Composite Modified Electrode and Application for Glucose Biosensing
  • 文献类型:   Article
  • 作  者:   PALANISAMY S, DEVASENATHIPATHY R, CHEN SM, ALI MA, KARUPPIAH C, BALAKUMAR V, PRAKASH P, ELSHIKH MS, ALHEMAID FMA
  • 作者关键词:   reduced graphene oxide, cyclodextrin, glucose oxidase, direct electrochemistry, glucose biosensor
  • 出版物名称:   ELECTROANALYSIS
  • ISSN:   1040-0397 EI 1521-4109
  • 通讯作者地址:   Natl Taipei Univ Technol
  • 被引频次:   14
  • DOI:   10.1002/elan.201500150
  • 出版年:   2015

▎ 摘  要

A simple glucose biosensor has been developed based on direct electrochemistry of glucose oxidase (GOx) immobilized on the reduced graphene oxide (RGO) and -cyclodextrin (CD) composite. A well-defined redox couple of GOx appears with a formal potential of approximate to-0.459V at RGO/CD composite. A heterogeneous electron transfer rate constant (K-s) has been calculated for GOx at RGO/CD as 3.8s(-1). The fabricated biosensor displays a wide response to glucose in the linear concentrations range from 50 mu M to 3.0mM. The sensitivity and limit of detection of the biosensor is estimated as 59.74 mu AmM(-1)cm(-2) and 12 mu M, respectively.