▎ 摘　　要

In this work, efforts have been made to develop a conducting paper- (CP) based biosensor using poly(3,4ethylenedioxythiophene): poly(4-styrene sulfonate) (PEDOT:PSS)-grafted reduced graphene oxide-titanium dioxide (rGO-TiO2) nanohybrid. The effect of different dopant (ethylene glycol [EG], glycerine and methanol) on the conductivity of the paper has been investigated, and it was observed that the conductivity of the CP significantly increases from 6.9 x 10(-5) S/cm to 1.1 x 10(-4) S/cm on treatment with EG. While, after the incorporation rGO-TiO2 nanohybrid into PEDOT:PSS-grafted paper, the conductivity increased to 4.9 x 10(-2) S/cm. The fabricated flexible rGO-TiO2@CP was characterized using X-ray diffraction, Thermogravimetric analysis, scanning electron microscopy, FTIR spectroscopy, and amperometric techniques. The developed rGO-TiO2@CP has been utilized for the immobilization of glucose oxidase for the quantitative estimation of glucose. Electrochemical results reveal that the modified CP shows high sensitivity (94.98 mu AmM-1 cm(-2)) with a low limit of detection (0.01 mM) and can be a promising substitute over other expensive conventional electrodes.