• 文献标题:   Graphene Sculpturene Nanopores for DNA Nucleobase Sensing
  • 文献类型:   Article
  • 作  者:   SADEGHI H, ALGARAGHOLY L, POPE T, BAILEY S, VISONTAI D, MANRIQUE D, FERRER J, GARCIASUAREZ V, SANGTARASH S, LAMBERT CJ
  • 作者关键词:  
  • 出版物名称:   JOURNAL OF PHYSICAL CHEMISTRY B
  • ISSN:   1520-6106 EI 1520-5207
  • 通讯作者地址:   Univ Lancaster
  • 被引频次:   33
  • DOI:   10.1021/jp5034917
  • 出版年:   2014

▎ 摘  要

To demonstrate the potential of nanopores in bilayer graphene for DNA sequencing, we computed the current-voltage characteristics of a bilayer graphene junction containing a nanopore and found that they change significantly when nucleobases are transported through the pore. To demonstrate the sensitivity and selectivity of example devices, we computed the probability distribution P-X(beta) of the quantity beta representing the change in the logarithmic current through the pore due to the presence of a nucleobase X (X = adenine, thymine, guanine, or cytosine). We quantified the selectivity of the bilayer-graphene nanopores by showing that P-X(beta) exhibits distinct peaks for each base X. To demonstrate that such discriminating sensing is a general feature of bilayer nanopores, the well-separated positions of these peaks were shown to be present for different pores, with alternative examples of electrical contacts.