• 文献标题:   New Composite Contrast Agents Based on Ln and Graphene Matrix for Multi-Energy Computed Tomography
  • 文献类型:   Article
  • 作  者:   SUSLOVA EV, KOZLOV AP, SHASHURIN DA, ROZHKOV VA, SOTENSKII RV, MAXIMOV SV, SAVILOV SV, MEDVEDEV OS, CHELKOV GA
  • 作者关键词:   graphene nanoflake, photoncounting computed tomography, multienergy computed tomography, contrast agents cas, lanthanide, support, functionalization, xray, nanoparticle
  • 出版物名称:   NANOMATERIALS
  • ISSN:  
  • 通讯作者地址:  
  • 被引频次:   0
  • DOI:   10.3390/nano12234110
  • 出版年:   2022

▎ 摘  要

The subject of the current research study is aimed at the development of novel types of contrast agents (CAs) for multi-energy computed tomography (CT) based on Ln-graphene composites, which include Ln (Ln = La, Nd, and Gd) nanoparticles with a size of 2-3 nm, acting as key contrasting elements, and graphene nanoflakes (GNFs) acting as the matrix. The synthesis and surface modifications of the GNFs and the properties of the new CAs are presented herein. The samples have had their characteristics determined using X-ray photoelectron spectroscopy, X-Ray diffraction, transmission electron microscopy, thermogravimetric analysis, and Raman spectroscopy. Multi-energy CT images of the La-, Nd-, and Gd-based CAs demonstrating their visualization and discriminative properties, as well as the possibility of a quantitative analysis, are presented.