• 文献标题:   Label Free DNA Detection Using Large Area Graphene Based Field Effect Transistor Biosensors
  • 文献类型:   Article
  • 作  者:   GUO SR, LIN J, PENCHEV M, YENGEL E, GHAZINEJAD M, OZKAN CS, OZKAN M
  • 作者关键词:   dna, biosensor, fet, functionalization, noncovalent
  • 出版物名称:   JOURNAL OF NANOSCIENCE NANOTECHNOLOGY
  • ISSN:   1533-4880 EI 1533-4899
  • 通讯作者地址:   Univ Calif Riverside
  • 被引频次:   42
  • DOI:   10.1166/jnn.2011.3885
  • 出版年:   2011

▎ 摘  要

We describe the fabrication of highly sensitive graphene based field effect transistor (FET) biosensors with a cost-effective approach and their application in label-free Deoxyribonucleic acid (DNA) detection. Chemical vapor deposition (CVD) grown graphene layers were used to achieve mass production of FET devices via conventional photolithographic patterning. Non-covalent functionalization of the graphene layer with 1-Pyrenebutanoic acid succinimidyl ester ensures high conductivity and sensitivity of the FET device. The present device could reach a detection limit as low as 3 X 10(-9) M.