▎ 摘　　要

Engineered nanomaterials continue to stimulate wide interest in diverse disciplines including electrochemistry. Particularly, nanomaterials continue to stimulate wide rare-earth-metal vanadate (REVO) is widely applied in the development of electrocatalyst. Therefore, we develop a new strategy for the fabrication of nanoarchitecture for an electrochemical sensor. A simple physical mixture method which allows precise control of the composition, structure, and surface morphology was adapted to synthesize europium vanadate/graphene oxide (EuV/GO) nanocomposites. The EuV/GO nanocomposites were analyzed using modern techniques and were potentially applied to electrochemical detection of neurodegenerative drug clioquinol (CQL). As electrode material for electrochemical sensor, EuV/GO showed a wide linear range (0.005-331; 345-1320 mu M) and very low limit of detection (0.001 mu M) with excellent selectivity. This nanoarchitecture prevents the electrode from fouling as well as acts as a bridge for rapid electron/ion transfer. In addition, the nanocomposites provide abundant active sites and large surface area to improve the channels between electrocatalyst and electrolyte. The practical applicability was revealed by quantifying the CQL concentration in biological sample, recommending this new approach as a reasonable alternative to the other traditional techniques. This REVO opens a new opportunity to build design for the family of electrode materials, which are used in electrochemical applications.